DNA Methylation and Its Impact on Biological Age

In the quest for longevity, understanding how to calculate your biological age is crucial. It’s important to unravel the genetic sequences that dictate our life expectancy. The scientific community has made significant advances in this field. DNA methylation has emerged as a key biomarker in the aging process. This complex science shows how our biological age may differ from the number of candles on our cake. It is shaped by both our inherited genetics and our daily choices.

Understanding DNA Methylation

DNA methylation is a biochemical process that involves the addition of a methyl group to the DNA molecule. This modification primarily occurs at cytosine bases followed by guanine (CpG sites). It is a critical component of the epigenetic machinery. It governs gene expression, cellular differentiation, and genome stability. As we age, these methylation patterns change. They serve as a quantifiable measure of our biological age through the “epigenetic clock.”

The Epigenetic Clock: A Measure of Biological Age

The epigenetic clock was developed by pioneers like Dr. Steve Horvath. It measures an individual’s biological age by evaluating the methylation state of specific DNA sites. Unlike chronological age, the biological clock is dynamic. It reflects the interaction between our genes and environment. It is a tool that predicts how many years we might live. It also estimates the quality of health we could enjoy during those years.

Lifestyle, Environment, and DNA Methylation

The dynamic nature of DNA methylation is strongly influenced by lifestyle and environmental factors. The foods we eat, the air we breathe, and the stress we endure affect epigenetics. They can lead to changes that either accelerate or decelerate our biological clock.

Diet and Nutrition: A diet rich in nutrients such as folate and B vitamins can promote healthy DNA methylation patterns. This impacts our biological age. Incorporating foods rich in polyphenols and omega-3 fatty acids is important. They can play a key role in maintaining youthful gene expression.

Physical Activity: Engaging in regular exercise can positively influence our epigenetic age. Activities ranging from brisk walking to HIIT workouts can be beneficial. They promote favorable DNA methylation patterns, associated with a youthful biological profile.

Stress and Psychological Well-being: Chronic stress can cause harmful changes in DNA methylation. It especially affects genes associated with the stress response. Mindfulness techniques and meditation can help manage stress. Potentially, they can rewind our biological clock.

Environmental Factors: Exposure to environmental toxins can alter methylation patterns. Reducing exposure and supporting detoxification systems is key. This helps protect our cellular health and biological age.

The Future of Biological Age and Research

By deciphering the relationship between our lifestyle and our biological clock, we gain power. We can reshape our health trajectory. Research on DNA methylation and aging is advancing rapidly. The potential for interventions that modify epigenetic marks to promote longevity is being discovered.

Conclusion

The quest to understand and influence our biological age is more than a scientific endeavor. It’s a pathway to better quality of life. By harnessing the power of epigenetics and understanding how to calculate our biological age, we can achieve much. We can unlock new possibilities for healthy aging and disease prevention. The epigenetic clock serves as a barometer for our biological age. It offers a more personalized roadmap for longevity that transcends the simple passage of chronological time.

We continue to explore the relationship between our biological clock and lifestyle choices. Technologies like the range of biological clocks from Eterna Diagnostics provide invaluable tools. They are useful for those seeking to understand their health. Through a combination of diet, exercise, stress reduction, and environmental awareness, we can significantly advance. Not only do we add years to our life, but also life to our years. Let’s keep the hands of our biological clock in harmony with our aspirations for a long and vibrant life.

More Articles

Subscription model

Access personalized, real-time tools to monitor your health and daily habits.

9,90 / month
99,90 / year

What does the subscription model include?

  • Manual upload of analytical results: Upload your old analyses easily and view your data in the app. At a glance you can see if your results are healthy and get deep insights.
  • Smartwatch connection: Check if your wearable device is compatible and connect it for full tracking.
  • Biometric data interpretation: Visualize physical activity and sport metrics in real time, checking if you are within optimal ranges for you.
  • Habits diary: Record your daily routine to detect patterns and improve your habits.
  • Speed of aging: Understand how your lifestyle affects your body and the way it ages using this proprietary metric.
  • Population comparison: Compare your habits and lifestyle with other Eterna users.
  • Knowledge Pills: Learn with exclusive educational content taught by health professionals.

Benefits of Subscribing

  • Real-time and personalized monitoring of your health.
  • Access to exclusive content and advanced tools.
  • Improve your habits thanks to daily interactive questionnaires.

How does it work?

1

Choose one of the two subscription models from our website or app.

2

Download the app, register and set up your profile.

3

Connect your smartwatch, upload your analytics and start monitoring your health.

Who is the target audience?

Ideal for those who want continuous, personalized, real-time monitoring of their health with advanced tools and recommendations.

Frequently Asked Questions

  • What devices can I connect? Compatible with most smartwatches and wearables on the market (see brands on home page).
  • When can I cancel my subscription? At any time, without penalties.
  • What type of content is included in the subscription? Educational pills, personalized recommendations and population-based comparisons.

Activate your subscription today and take the first step towards comprehensive health care.

Plan Élite

La experiencia definitiva: acceso completo a todas las herramientas de Eterna Diagnostics, test de edad biológica, consultas médicas y eventos exclusivos.

La solución más completa para la prevención del riesgo de enfermedades, combinando la información más avanzada, soporte médico continuo y recursos exclusivos para potenciar tu longevidad y bienestar.

985,00 €

¿Qué incluye el Plan ProAge?

1. Test AgeScan Full

Nuestro test personalizado más completo. Mediante un análisis de más de 30 biomarcadores podrás evaluar tu salud general y niveles hormonales de manera completa. Los biomarcadores que analizamos son:

  • ALB: Albúmina
  • ALP: Fosfatasa alcalina
  • APOB: Apolipoproteína B
  • CA: Calcio total
  • CHOL: Colesterol total
  • CISTATINAC: Cistatina C
  • CK: Creatin quinasa
  • CREA: Creatinina
  • E2: Estradiol
  • FE: Hierro
  • FERRI: Ferritina
  • FR: Recuento celular/fórmula hematológica
  • GGT: Gammaglutamiltranspeptidasa
  • GLU: Glucosa
  • GOT: Aspartato aminotransferasa
  • GPT: Alanina aminotransferasa
  • HBA1C: Hemoglobina A1c
  • HDL: HDL Colesterol
  • HOMOCISTE: Homocisteína
  • INSU: Insulina
  • ISATUFE: Índice saturación transferrina
  • K: Potasio
  • LDL: LDL Colesterol
  • LPA: Lipoproteína (a)
  • MG: Magnesio
  • NA: Sodio
  • PCR: Proteína C reactiva (hs)
  • SHBG: Sex hormone binding globulin
  • TESTOS: Testosterona total
  • TESTOSLI: Testosterona libre
  • TRANSF: Transferrina
  • TRI: Triglicéridos
  • URI: Ácido úrico
  • VITAD25: Vitamina D 25-hidroxi
  • VLDL: VLDL colesterol

2. Análisis Genético

Descubre predisposiciones genéticas clave para personalizar aún más tus hábitos de salud y bienestar.

3. Test ProAge de Edad Biológica

Determina tu edad biológica basada en biomarcadores sanguíneos relacionados con la salud cardiovascular, el sistema inmune, el cáncer y la salud metabólica. También obtendrás información valiosa sobre cómo optimizar tu envejecimiento.

4. Consultas Médicas

Accede a consultas con profesionales médicos para interpretar tus resultados y diseñar estrategias de mejora personalizadas.

5. Resolución de dudas

Recibe orientación de especialistas para interpretar tus resultados y establecer estrategias personalizadas.

6. Acceso Premium a la App (12 meses)

Disfrutarás de 12 meses de suscripción a la app, incluyendo todas las funcionalidades que se encuentran en el modelo de suscripción:

  • Subida manual de resultados de analíticas
  • Conexión de smartwatch
  • Interpretación de datos biométricos
  • Diario de hábitos
  • Velocidad de envejecimiento
  • Comparativa poblacional
  • Píldoras de Conocimiento

Beneficios de este plan

  • Visión completa de tu salud con un panel analítico de más de 30 biomarcadores a bajo coste.
  • Acceso a herramientas digitales para un monitorización de tu salud en tiempo real.
  • Integración de una nueva ciencia ómica (genética) en la visión holística de tu salud.
  • La evaluación más completa: biomarcadores, análisis genético y test de edad biológica.
  • Consultas médicas para diseñar estrategias personalizadas.

¿Cómo funciona?

1

Compra el Plan Élite, descarga la app y activa tus tests.

2

Reserva tu cita para AgeScanFull y el test genético, acude al laboratorio (6h de ayuno necesarias en el caso de AgeScan Full) e identifícate con tu código personal antes de realizar tus tests. Resultados en un plazo máximo de 30 días en la app/web (90 días en el caso de nuestro test genético).

3

Selecciona fecha y hora para la recogida del test ProAge de Edad Biológica. El test se entrega y se recoge a domicilio, sigue las instrucciones que encontrarás en el interior del producto.

4

Conecta tu wearable y monitoriza tus hábitos en tiempo real.

¿A quién va dirigido?

Para quienes buscan un enfoque integral y profesional en el cuidado de su salud, combinando análisis biométricos, bioquímicos, proteómicos, genéticos, test de edad biológica y asesoramiento médico personalizado.

Preguntas Frecuentes

  • ¿Qué necesito si quiero obtener mi Plan Pro? Ayuna 6h antes de llegar al laboratorio para hacerte la analítica (sólo necesario para el test AgeScan Full) y lleva tu código de identificación.
  • ¿Cuándo tendré mis resultados? En un máximo de 30 días, estarán visibles en la app/web (90 días en el caso del test genético).
  • ¿Qué incluye el asesoramiento personalizado? Sesiones con especialistas para interpretar resultados y optimizar hábitos.
  • ¿Qué pasa cuando terminan los 12 meses de suscripción a la app incluidos en el Plan Pro? Deberás renovar tu suscripción (mediante el modelo de suscripción) o comprar otro Plan para continuar monitorizando tu salud.
  • ¿Qué necesito para hacerme el Test ProAge de Edad Biológica? Lo podrás realizar desde tu casa, siguiendo las instrucciones que encontrarás en el paquete. Solicita la recogida desde la app y nuestro servicio logístico se encargará.
  • ¿En qué consiste el Test ProAge de Edad Biológica? Consiste en la evaluación de la edad biológica real de tu cuerpo (mucho más precisa que la edad cronológica) basada en biomarcadores clave.

Lo que opinan nuestros usuarios

"Con ProAge, he podido conocer mi edad biológica y correlacionarla con mi frenético estilo de vida. Este valor también estaba estrechamente relacionado con mis predisposiciones genéticas y con los resultados de mi Test AgeScan Full. Ya he tenido una consulta con el médico especialista de Eterna y me ha dado pautas para revertir mis resultados y empezar a rejuvener. Una tecnología realmente sorprendente." – Carlos, 60 años.

Empieza hoy a cuidar tu salud con Eterna. Una decisión sencilla, un gran paso hacia tu bienestar.

Pro Plan

Take your monitoring to the next level with advanced analytics, biological age tests, personalized consultations and access to our private community.

Get the most out of preventing disease with a comprehensive approach, backed by multi-omics data and expert advice, reducing risk and improving your long-term health.

784,00 €

What does the Pro Plan include?

AgeScan Advanced Test

Our most complete personalized test. Through an analysis of more than 30 biomarkers you will be able to evaluate your general health and hormone levels in a complete way. The biomarkers we analyze are:

  • ALB: Albumin
  • ALP: Alkaline Phosphatase
  • APOB: Apolipoprotein B
  • CA: Total calcium
  • CHOL: Total cholesterol
  • CYSTATINAC: Cystatin C
  • CK: Creatine kinase
  • CREA: Creatinine
  • E2: Estradiol
  • FE: Iron
  • FERRI: Ferritin
  • FR: Cell count/hematologic formula
  • GGT: Gamma-glutamyltranspeptidase
  • GLU: Glucose
  • GOT: Aspartate Aminotransferase
  • GPT: Alanine aminotransferase
  • HBA1C: Hemoglobin A1c
  • HDL: HDL Cholesterol
  • HOMOCysteine: Homocysteine
  • INSU: Insulin
  • ISATUFE: Transferrin Saturation Index
  • K: Potassium
  • LDL: LDL Cholesterol
  • LPA: Lipoprotein (a)
  • MG: Magnesium
  • NA: Sodium
  • PCR: C-reactive protein (hs)
  • SHBG: Sex hormone binding globulin
  • TESTS: Total testosterone
  • TESTOSLI: Free testosterone
  • TRANSF: Transferrin
  • TRI: Triglycerides
  • URI: Uric acid
  • VITAD25: 25-hydroxy vitamin D
  • VLDL: VLDL cholesterol

Resolution of doubts

Receive guidance from specialists to interpret your results and establish personalized strategies.

3. Premium App Access (12 months)

You will enjoy a 12-month subscription to the app, including all the features found in the subscription model:

  • Manual upload of analysis results
  • Smartwatch connection
  • Interpretation of biometric data
  • Habits diary
  • Aging rate
  • Population comparison
  • Knowledge Pills

3. ProAge Biological Age Test

Determine your biological age based on blood biomarkers related to cardiovascular, immune, cancer and metabolic health. You will also gain valuable information on how to optimize your aging.

4. Medical Consultations

Access consultations with medical professionals to interpret your results and design personalized improvement strategies.

Benefits of this plan

  • Complete vision of your health with an analytical panel of more than 30 biomarkers at low cost.
  • Access to digital tools to monitor your health in real time.
  • Integration of new omic sciences for a holistic vision of your health.
  • The most complete evaluation: biological age test.
  • Medical consultations to design personalized strategies.

How does it work?

1

Purchase the Pro Plan, download the app and activate your tests.

2

Book your appointment for AgeScan Advanced, come to the lab (6h fasting required) and identify yourself with your personal code before performing your tests. Results within 30 days on the app/web.

3

Select date and time for the collection of the ProAge Biological Age test. The test is delivered and picked up at home, follow the instructions inside the product.

4

Connect your wearable and monitor your habits in real time.

Who is the target audience?

Ideal for those who wish to deepen their health care with personalized analysis, advanced tools and expert support.

Frequently Asked Questions

  • What do I need to do before going to the lab to get AgeScan Advanced? Fast 6h before arriving at the laboratory and bring your identification code.
  • When will I get my results? In a maximum of 30 days, they will be visible on the app/web.
  • What does personalized consulting include? Sessions with specialists to interpret results and optimize habits.
  • What happens when the 12-month app subscription included in the Pro Plan expires? You will need to renew your subscription (using the subscription model) or purchase another Plan to continue monitoring your health.

What our users say

"Thanks to Eterna's Pro Plan I have been able to correlate my lifestyle with my daily routines, understanding many doubts I had. I have also found out why my biological age was higher than my chronological age and I have managed to reverse it" - Juan, 64 years old.

Start taking care of your health today with Eterna. A simple decision, a big step towards your wellbeing.

Advanced Plan

Expand your knowledge of your body: get more data with our AgeScan Advanced biomarker panel and a 6-month subscription to our monitoring app.

A plan that helps you deepen your prevention of chronic disease risk , identifying key factors early and optimizing your habits for a fuller life.

197,00 €

What does the Advanced Plan include?

AgeScan Advanced Test

Our most complete personalized test. Through an analysis of more than 30 biomarkers you will be able to evaluate your general health and hormone levels in a complete way. The biomarkers we analyze are:

  • ALB: Albumin
  • ALP: Alkaline Phosphatase
  • APOB: Apolipoprotein B
  • CA: Total calcium
  • CHOL: Total cholesterol
  • CYSTATINAC: Cystatin C
  • CK: Creatine kinase
  • CREA: Creatinine
  • E2: Estradiol
  • FE: Iron
  • FERRI: Ferritin
  • FR: Cell count/hematologic formula
  • GGT: Gamma-glutamyltranspeptidase
  • GLU: Glucose
  • GOT: Aspartate Aminotransferase
  • GPT: Alanine aminotransferase
  • HBA1C: Hemoglobin A1c
  • HDL: HDL Cholesterol
  • HOMOCysteine: Homocysteine
  • INSU: Insulin
  • ISATUFE: Transferrin Saturation Index
  • K: Potassium
  • LDL: LDL Cholesterol
  • LPA: Lipoprotein (a)
  • MG: Magnesium
  • NA: Sodium
  • PCR: C-reactive protein (hs)
  • SHBG: Sex hormone binding globulin
  • TESTS: Total testosterone
  • TESTOSLI: Free testosterone
  • TRANSF: Transferrin
  • TRI: Triglycerides
  • URI: Uric acid
  • VITAD25: 25-hydroxy vitamin D
  • VLDL: VLDL cholesterol

2. Premium App Access (6 months)

You will enjoy 6 months of subscription to the app, including all the functionalities found in the subscription model:

  • Manual upload of analysis results
  • Smartwatch connection
  • Interpretation of biometric data
  • Habits diary
  • Aging rate
  • Population comparison
  • Knowledge Pills

Benefits of choosing this plan

  • Complete vision of your health with an analytical panel of more than 30 biomarkers at low cost.
  • Access to digital tools to monitor your health in real time.
  • You will be able to discover patterns in your lifestyle and optimize your well-being.

How does it work?

1

Purchase the Advanced Plan, download the app and activate your test.

2

Book your appointment, go to the laboratory after 6 hours of fasting identifying yourself with your personal code, and perform the test. Results within 30 days in the app/web.

3

Connect your wearable and start monitoring your habits in real time.

Who is the target audience?

Ideal for those who want a detailed analysis of the biological state of their organism and at the same time a continuous monitoring with advanced tools to improve their well-being.

Frequently Asked Questions

  • What do I need to do before going to the lab to get AgeScan Advanced? Fast 6h before arriving at the laboratory and bring your identification code.
  • When will I get my results? In a maximum of 30 days, they will be visible on the app/web.
  • What happens when the 6 months app subscription included in the Advanced Plan expires? You will need to renew your subscription (using the subscription model) or purchase another Plan to continue monitoring your health.

What our users say

"Thanks to Eterna Diagnostics and its Advanced Plan, I maintain an ideal lifestyle thanks to the constant monitoring of all the parameters that interest me, and without the need to go to the doctor. I am delighted." - Juan, 51 years old.

Start taking care of your health today with Eterna. A simple decision, a big step towards your wellbeing.

Basic Plan

Start your path to better wellness with our essential tools and an initial analysis of your health status.

The first step for the prevention and reduction of the risk of suffering diseases, oriented to a sustainable improvement of your quality of life.

48,00 €

What does the Basic Plan include?

1. AgeScan Test

With this biological test, specifically developed by Eterna Diagnostics, you will obtain a detailed analysis of 20 essential biomarkers for the organism:

  • ALB: Albumin
  • ALP: Alkaline Phosphatase
  • CA: Total calcium
  • CHOL: Total cholesterol
  • CREA: Creatinine
  • FE: Iron
  • FERRI: Ferritin
  • FR: Hematological formula
  • GGT: Gamma-glutamyltranspeptidase
  • GLU: Glucose
  • GOT: Aspartate Aminotransferase
  • GPT: Alanine aminotransferase
  • HDL: HDL Cholesterol
  • K: Potassium
  • LDL: LDL Cholesterol
  • NA: Sodium
  • PCR: C-reactive protein (hs)
  • TRANSF: Transferrin
  • TRI: Triglycerides
  • URI: Uric acid

2. Premium App Access (3 months)

You will enjoy a 3-month subscription to the app, including all the features found in the subscription model:

  • Manual upload of analysis results
  • Smartwatch connection
  • Interpretation of biometric data
  • Habits diary
  • Aging rate
  • Population comparison
  • Knowledge Pills

Benefits of this plan

  • Essential health check-up at a competitive cost.
  • Early detection of possible alterations (cholesterol, glucose, iron, etc.).
  • Holistic and real-time monitoring with our app.

How does it work?

1

Purchase the Basic Plan, download the app and activate your test.

2

Book your appointment, go to the laboratory after 6 hours of fasting identifying yourself with your personal code, and perform the test. Results within 30 days in the app/web.

3

Connect your wearable and start monitoring your habits in real time.

Who is the target audience?

Ideal for those who wish to take the first step towards a more conscious care of their health, integrating classic biomarkers of biological monitoring with functional lifestyle parameters.

Frequently Asked Questions

  • What do I need to do before going to the lab to get an AgeScan? Fast 6h before arriving at the laboratory and bring your identification code.
  • When will I get my results? In a maximum of 30 days, they will be visible on the app/web.
  • What happens when the 3-month app subscription included in the Basic Plan expires? You will need to renew your subscription (using the subscription model) or purchase another Plan to continue monitoring your health.

What our users say

"I detected an iron deficiency early thanks to the Eterna app. Now I can explain my poor sports performance." - Maria, 35 years old.
"I can see how my habits influence my well-being, it's very revealing." - Jorge, 42 years old.

Start taking care of your health today with Eterna. A simple decision, a big step towards your wellbeing.