Research in epigenetics has revolutionized our understanding of biological age. Now, we have a new perspective that goes beyond chronological age. Advances in molecular biology have been key to discovering epigenetics-based predictors, essential for understanding the mechanisms of aging.
The Revolution of Biomarkers in Aging
The biomarkers of biological age, based on epigenetics, provide valuable information about the impact of genetic, environmental, and lifestyle factors. Among these predictors are epigenetic clocks, telomere length, and transcriptomic, proteomic, and metabolomic analyses. These are crucial for evaluating how we age.
GrimAge: The Star Epigenetic Clock
Among the epigenetics-based clocks, GrimAge stands out for its remarkable precision. It can predict health and longevity better than other clocks such as Horvath and Hannum. This predictor closely relates to key health indicators.
ETERNA and Epigenetic Science
At ETERNA, we consider epigenetics a fundamental pillar. We develop products that modulate DNA methylation, providing strategies for healthy aging.
Commitment to Innovation
Our focus on innovation is based on epigenetic science. We design products that harmoniously integrate with the body’s epigenetic mechanisms, promoting overall well-being.
Conclusion: Towards a New Era in Precision Medicine
Epigenetics-based clocks, especially GrimAge, are paving the way for precision medicine. This significantly improves our quality of life and marks the beginning of a new era in personalized care.
References
- Jylhävä J, Pedersen NL, Hägg S. Biological Age Predictors. EBioMedicine. 2017 Jul;21:29-36. doi: 10.1016/j.ebiom.2017.03.046. Epub 2017 Apr 1. PMID: 28396265; PMCID: PMC5514388.
- Cathal McCrory, PhD and others, GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality, The Journals of Gerontology: Series A, Volume 76, Issue 5, May 2021, Pages 741–749, https://doi.org/10.1093/gerona/glaa286
- Lu AT, Quach A, Wilson JG, Reiner AP, Aviv A, Raj K, Hou L, Baccarelli AA, Li Y, Stewart JD, Whitsel EA, Assimes TL, Ferrucci L, Horvath S. DNA methylation GrimAge strongly predicts lifespan and healthspan. Aging (Albany NY). 2019 Jan 21;11(2):303-327. doi: 10.18632/aging.101684. PMID: 30669119; PMCID: PMC6366976.
